Aspartate beta Hydroxylase 抗体 (AA 111-270)
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- 抗原 See all Aspartate beta Hydroxylase (ASPH) 抗体
- Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
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抗原表位
- AA 111-270
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aspartate beta Hydroxylase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ERSTSEPAVP PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHETEHSYH VEETVSQDCN QDMEEMMSEQ ENPDSSEPVV EDERLHHDTD DVTYQVYEEQ AVYEPLENEG IEITEVTAPP EDNPVEDSQV IVEEVSIFPV EEQQEVPPDT
- 交叉反应
- 人
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 111-270 of human ASPH (NP_001158227.1).
- 亚型
- IgG
- Top Product
- Discover our top product ASPH Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
- 别名
- ASPH (ASPH 产品)
- 背景
- This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.,ASPH,AAH,BAH,CASQ2BP1,FDLAB,HAAH,JCTN,junctin,Signal Transduction,Neuroscience,Calcium Signaling,ASPH
- 分子量
- 21-34 kDa/83-85 kDa
- 基因ID
- 444
- UniProt
- Q12797
- 途径
- Positive Regulation of Endopeptidase Activity
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