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ASCC2 抗体 (AA 488-757)
ASCC2
适用: 人
WB, IHC
宿主: 兔
Polyclonal
unconjugated
ASCC2抗体详情
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抗原
See all ASCC2 抗体
ASCC2
(Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2))
抗原表位
All epitopes for ASCC2 抗体
AA 488-757
适用
All reactivities for ASCC2 抗体
人
宿主
All hosts for ASCC2 抗体
兔
克隆类型
All clonalities for ASCC2 抗体
多克隆
标记
All conjugates for ASCC2 抗体
This ASCC2 antibody is un-conjugated
应用范围
All applications for ASCC2 抗体
Western Blotting (WB), Immunohistochemistry (IHC)
序列
LACLEYYHYD PEQVINNILE ERLAPTLSQL DRNLDREMKP DPTPLLTSRH NVFQNDEFDV FSRDSVDLSR VHKGKSTRKE ENTRSLLNDK RAVAAQRQRY EQYSVVVEEV PLQPGESLPY HSVYYEDEYD DTYDGNQVGA NDADSDDELI SRRPFTIPQV LRTKVPREGQ EEDDDDEEDD ADEEAPKPDH FVQDPAVLRE KAEARRMAFL AKKGYRHDSS TAVAGSPRGH GQSRETTQER RKKEANKATR ANHNRRTMAD RKRSKGMIPS
交叉反应
人, 小鼠, 大鼠
产品特性
Polyclonal Antibodies
纯化方法
Affinity purification
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 488-757 of human ASCC2 (NP_115580.2).
亚型
IgG
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Discover our top product ASCC2 Primary Antibody
Alternatives
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anti-Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2) (AA 612-661) antibody
ASCC2
适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, Bat, 小鸡, Hamster, 猴, 非洲爪蟾
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB,1:500 - 1:2000,IHC,1:50 - 1:100
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
ASCC2目标详情
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抗原
ASCC2
(Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2))
别名
ASCC2 (ASCC2 产品 )
别名
MGC63666 antibody, zgc:63666 antibody, ASCC2 antibody, ascc2 antibody, asc1p100 antibody, ASC1p100 antibody, p100 antibody, 1700011I11Rik antibody, 2610034L15Rik antibody, AI482016 antibody, AW046480 antibody, RGD1561422 antibody, activating signal cointegrator 1 complex subunit 2 antibody, activating signal cointegrator 1 complex subunit 2 S homeolog antibody, ascc2 antibody, ASCC2 antibody, MCYG_08331 antibody, ascc2.S antibody, Ascc2 antibody
背景
Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. Involved in activation of the ribosome quality control (RQC pathway, a pathway that degrades nascent peptide chains during problematic translation. As part of the ribosome quality control trigger (RQT complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes (By similarity.,ASCC2,ASC1p100,p100,Signal Transduction,ASCC2
分子量
41 kDa/77 kDa/86 kDa
基因ID
84164
UniProt
Q9H1I8
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