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ARHGAP44 抗体 (AA 666-772)

ARHGAP44 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6137082
发货至: 中国
  • 抗原 See all ARHGAP44 抗体
    ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))
    抗原表位
    • 8
    • 8
    • 7
    • 2
    • 1
    AA 666-772
    适用
    • 22
    • 6
    • 5
    宿主
    • 22
    克隆类型
    • 22
    多克隆
    标记
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    This ARHGAP44 antibody is un-conjugated
    应用范围
    • 21
    • 17
    • 15
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    MADQSAGQPS PVSLSPTPPS TPSPYGLSYP QGYSLASGQL SPAAAPPLAS PSVFTSTLSK SRPTPKPRQR PTLPPPQPPT VNLSASSPQS TEAPMLDGMS PGESMST
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 666-772 of human ARHGAP44 (NP_055674.4).
    亚型
    IgG
    Top Product
    Discover our top product ARHGAP44 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))
    别名
    ARHGAP44 (ARHGAP44 产品)
    别名
    RICH2 antibody, arhgap44 antibody, NPC-A-10 antibody, 6330543G20 antibody, AI840762 antibody, AU040829 antibody, AW493732 antibody, Rich2 antibody, Rho GTPase activating protein 44 antibody, si:ch211-114m9.1 antibody, ARHGAP44 antibody, si:ch211-114m9.1 antibody, Arhgap44 antibody
    背景
    GTPase-activating protein (GAP that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. Acts as a GAP at least for CDC42 and RAC1. In neurons, is involved in dendritic spine formation and synaptic plasticity in a specific RAC1-GAP activity (By similarity. Limits the initiation of exploratory dendritic filopodia. Recruited to actin-patches that seed filopodia, binds specifically to plasma membrane sections that are deformed inward by acto-myosin mediated contractile forces. Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation (By similarity. In association with SHANK3, promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation (By similarity.,ARHGAP44,NPC-A-10,RICH2,Signal Transduction,G protein signaling,Signal Transduction,ARHGAP44
    分子量
    83 kDa/88 kDa/89 kDa
    基因ID
    9912
    UniProt
    Q17R89
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