×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
APEX1 抗体 (AA 1-318)
APEX1
适用: 人
WB, IF, IP
宿主: 兔
Polyclonal
unconjugated
APEX1抗体详情
(hide)
抗原
See all APEX1 抗体
APEX1
(Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
抗原表位
All epitopes for APEX1 抗体
AA 1-318
适用
All reactivities for APEX1 抗体
人
宿主
All hosts for APEX1 抗体
兔
克隆类型
All clonalities for APEX1 抗体
多克隆
标记
All conjugates for APEX1 抗体
This APEX1 antibody is un-conjugated
应用范围
All applications for APEX1 抗体
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
序列
MPKRGKKGAV AEDGDELRTE PEAKKSKTAA KKNDKEAAGE GPALYEDPPD QKTSPSGKPA TLKICSWNVD GLRAWIKKKG LDWVKEEAPD ILCLQETKCS ENKLPAELQE LPGLSHQYWS APSDKEGYSG VGLLSRQCPL KVSYGIGDEE HDQEGRVIVA EFDSFVLVTA YVPNAGRGLV RLEYRQRWDE AFRKFLKGLA SRKPLVLCGD LNVAHEEIDL RNPKGNKKNA GFTPQERQGF GELLQAVPLA DSFRHLYPNT PYAYTFWTYM MNARSKNVGW RLDYFLLSHS LLPALCDSKI RSKALGSDHC PITLYLAL
交叉反应
人
产品特性
Polyclonal Antibodies
纯化方法
Affinity purification
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1/APE1 (NP_542380.1).
亚型
IgG
Top Product
Discover our top product APEX1 Primary Antibody
Alternatives
(show)
使用细节
(hide)
应用备注
WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:50 - 1:200
限制
仅限研究用
贮存及处理
(hide)
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
APEX1目标详情
(hide)
抗原
APEX1
(Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
别名
APEX1 (APEX1 产品 )
别名
apex1 antibody, MGC76280 antibody, MGC79645 antibody, MGC78928 antibody, APE antibody, APE1 antibody, APEN antibody, APEX antibody, APX antibody, HAP1 antibody, REF1 antibody, Apex antibody, REF-1 antibody, BAP1 antibody, apex1a antibody, hm:zehn1532 antibody, wu:fc13d11 antibody, zgc:66204 antibody, Ref-1 antibody, apurinic/apyrimidinic endodeoxyribonuclease 1 antibody, APEX nuclease (multifunctional DNA repair enzyme) 1 antibody, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog antibody, DNA-(apurinic or apyrimidinic site) lyase antibody, apurinic/apyrimidinic endonuclease 1 antibody, APEX1 antibody, apex1 antibody, apex1.L antibody, CNG03640 antibody, CNH01280 antibody, nth antibody, Spirs_4119 antibody, Palpr_0103 antibody, Apex1 antibody
背景
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein.,APEX1,APE,APE1,APEN,APEX,APX,HAP1,REF1,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cardiovascular,Heart,Cardiogenesis,APEX1
分子量
35 kDa
基因ID
328
UniProt
P27695
途径
DNA Damage Repair , Chromatin Binding , Cell RedoxHomeostasis , Smooth Muscle Cell Migration , Positive Regulation of Response to DNA Damage Stimulus
Recently viewed
(hide)