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Aminoacylase 1 抗体 (AA 1-408)

ACY1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6136509
发货至: 中国
  • 抗原 See all Aminoacylase 1 (ACY1) 抗体
    Aminoacylase 1 (ACY1)
    抗原表位
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-408
    适用
    • 31
    • 14
    • 4
    • 2
    • 2
    • 1
    宿主
    • 21
    • 12
    • 2
    克隆类型
    • 23
    • 12
    多克隆
    标记
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aminoacylase 1 antibody is un-conjugated
    应用范围
    • 25
    • 14
    • 12
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    MTSKGPEEEH PSVTLFRQYL RIRTVQPKPD YGAAVAFFEE TARQLGLGCQ KVEVAPGYVV TVLTWPGTNP TLSSILLNSH TDVVPVFKEH WSHDPFEAFK DSEGYIYARG AQDMKCVSIQ YLEAVRRLKV EGHRFPRTIH MTFVPDEEVG GHQGMELFVQ RPEFHALRAG FALDEGIANP TDAFTVFYSE RSPWWVRVTS TGRPGHASRF MEDTAAEKLH KVVNSILAFR EKEWQRLQSN PHLKEGSVTS VNLTKLEGGV AYNVIPATMS ASFDFRVAPD VDFKAFEEQL QSWCQAAGEG VTLEFAQKWM HPQVTPTDDS NPWWAAFSRV CKDMNLTLEP EIMPAATDNR YIRAVGVPAL GFSPMNRTPV LLHDHDERLH EAVFLRGVDI YTRLLPALAS VPALPSDS
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-408 of human ACY1 (NP_001185824.1).
    亚型
    IgG
    Top Product
    Discover our top product ACY1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Aminoacylase 1 (ACY1)
    别名
    ACY1 (ACY1 产品)
    别名
    si:zfos-226g1.1 antibody, zgc:55605 antibody, zgc:76955 antibody, acy1 antibody, acy1d antibody, acylase antibody, ACY1 antibody, ACY-1 antibody, ACY1D antibody, 1110014J22Rik antibody, Acy-1 antibody, Acy1a antibody, Acy1b antibody, aminoacylase 1 antibody, aminoacylase 1, gene 1 S homeolog antibody, aminoacylase 1, gene 1 antibody, ACY1 antibody, acy1 antibody, acy1.1.S antibody, acy1.1 antibody, Acy1 antibody
    背景
    This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.,ACY1,ACY-1,ACY1D,HEL-S-5,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,ACY1
    分子量
    37 kDa/38 kDa/42 kDa/45 kDa
    基因ID
    95
    UniProt
    Q03154
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