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ABAT 抗体 (AA 29-300)

ABAT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6136330
发货至: 中国
  • 抗原 See all ABAT 抗体
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    抗原表位
    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-300
    适用
    • 44
    • 31
    • 30
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 40
    • 5
    克隆类型
    • 39
    • 6
    多克隆
    标记
    • 25
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABAT antibody is un-conjugated
    应用范围
    • 37
    • 13
    • 13
    • 13
    • 11
    • 9
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    SQAAAKVDVE FDYDGPLMKT EVPGPRSQEL MKQLNIIQNA EAVHFFCNYE ESRGNYLVDV DGNRMLDLYS QISSVPIGYS HPALLKLIQQ PQNASMFVNR PALGILPPEN FVEKLRQSLL SVAPKGMSQL ITMACGSCSN ENALKTIFMW YRSKERGQRG FSQEELETCM INQAPGCPDY SILSFMGAFH GRTMGCLATT HSKAIHKIDI PSFDWPIAPF PRLKYPLEEF VKENQQEEAR CLEEVEDLIV KYRKKKKTVA GIIVEPIQSE GG
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 29-300 of human GABA transaminase (GABA transaminase (ABAT)) (NP_001120920.1).
    亚型
    IgG
    Top Product
    Discover our top product ABAT Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zeng, Yang, Du, Li, Shen, Liu, Chen, Kamal, Guan, Cheng, Wang, Xu: "Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats." in: Oncotarget, Vol. 8, Issue 60, pp. 102020-102032, (2017) (PubMed).

  • 抗原
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    别名
    ABAT (ABAT 产品)
    背景
    4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.,ABAT,GABA-AT,GABAT,NPD009,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,Neuroscience,Neurodegenerative Diseases Markers,Other Neurological disorders,ABAT
    分子量
    56 kDa
    基因ID
    18
    UniProt
    P80404
    途径
    Monocarboxylic Acid Catabolic Process
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