The mouse monoclonal antibody V65 recognizes an extracellular epitope of TCR gamma/delta, the subtype of T cell receptor expressed mainly in epithelial tissues and at the sites of infection.
交叉反应 (详细)
Rat
纯化方法
Purified by protein-A affinity chromatography.
纯度
> 95 % (by SDS-PAGE)
免疫原
TCR alpha/beta-negative CD3-positive rat T cell hybridoma III.89.1.4 line
TCR gamma/delta
FACS, IF
宿主: Armenian Hamster
Monoclonal
UC7-13D5
FITC
应用备注
Flow cytometry: Recommended dilution: 1 μg/mL.
限制
仅限研究用
浓度
1 mg/mL
缓冲液
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Do not freeze.
储存条件
4 °C
储存方法
Store at 2-8°C. Do not freeze.
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The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRG/D