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CaMKIIbeta/gamma/delta 抗体 (pThr287)

适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5960666
发货至: 中国
  • 抗原 See all CaMKIIbeta/gamma/delta products
    CaMKIIbeta/gamma/delta
    抗原表位
    • 3
    • 1
    • 1
    • 1
    pThr287
    适用
    人, 小鼠, 大鼠
    宿主
    • 4
    • 1
    克隆类型
    • 4
    • 1
    多克隆
    标记
    • 5
    This CaMKIIbeta/gamma/delta antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    CAMK2B,CAM2,CAMK2,CAMKB,Calcium/calmodulin-dependent protein kinase type II subunit beta,CaM kinase II subunit beta,CaMK-II subunit beta,CAMK2G,CAMK,CAMK-II,CAMKG,Calcium/calmodulin-dependent protein kinase type II subunit gamma,
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from human CaMKIIbeta/gamma/delta around the phosphorylation site of Thr287
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:5000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CaMKIIbeta/gamma/delta
    Abstract
    CaMKIIbeta/gamma/delta 产品
    背景
    The product of CAMK2B belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) is a Protein Coding gene. Diseases associated with CAMK2B include Phencyclidine Abuse. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2G. The product of CAMK2G is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined. CAMK2G (Calcium/Calmodulin Dependent Protein Kinase II Gamma) is a Protein Coding gene. Diseases associated with CAMK2G include Timothy Syndrome and Exudative Vitreoretinopathy. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2B. The product of CAMK2D belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.CAMK2D (Calcium/Calmodulin Dependent Protein Kinase II Delta) is a Protein Coding gene. Diseases associated with CAMK2D include Dilated Cardiomyopathy and Cardiomyopathy. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2B.
    分子量
    56-72kDa
    基因ID
    816, 818, 817
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