电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CaMKIIalpha/delta 抗体 (Thr286)

适用: 人, 小鼠, 大鼠 IF, WB, IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5960662
发货至: 中国
  • 抗原 See all CaMKIIalpha/delta products
    CaMKIIalpha/delta
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    Thr286
    适用
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 6
    克隆类型
    • 6
    多克隆
    标记
    • 6
    This CaMKIIalpha/delta antibody is un-conjugated
    应用范围
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    特异性
    CAMK2A,CAMKA,KIAA0968,Calcium/calmodulin-dependent protein kinase type II subunit alpha,CaM kinase II subunit alpha,CaMK-II subunit alpha,CAMK2D,CAMKD,Calcium/calmodulin-dependent protein kinase type II subunit delta,CaM kinase II
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from human CaMKIIalpha/delta around the non-phosphorylation site of Thr286.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CaMKIIalpha/delta
    Abstract
    CaMKIIalpha/delta 产品
    背景
    The product of CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.CAMK2A (Calcium/Calmodulin Dependent Protein Kinase II Alpha) is a Protein Coding gene. Diseases associated with CAMK2A include Conduct Disorder. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2D. The product of CAMK2D belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.CAMK2D (Calcium/Calmodulin Dependent Protein Kinase II Delta) is a Protein Coding gene. Diseases associated with CAMK2D include Dilated Cardiomyopathy and Cardiomyopathy. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2B.
    分子量
    54kDa
    基因ID
    815, 817
You are here:
客服