Western Blotting (WB), Immunohistochemistry (IHC), ELISA
特异性
Endoplasmic reticulum resident protein 44,Endoplasmic reticulum resident protein 44 kDa,Endoplasmic reticulum resident protein ERp44,ER protein 44,ERp44,ERP44,KIAA0573,PDIA10,Protein disulfide isomerase family A,member 10,Thioredoxin domain containing 4 (endoplasmic reticulum),Thioredoxin domain containing protein 4,Thioredoxin domain-containing protein 4,UNQ532/PRO1075
ERP44 is a 406 amino acid protein that contains one thioredoxin domain, a motif that participates in various redox reactions throughout the cell. Localized to the lumen of the endoplasmic reticulum (ER), TXNDC4 functions to inhibit the activity of IP3R-I (inositol 1,4,5-triphosphate receptor,type 1) within calcium channels. In addition, TXNDC4 is thought to regulate oxidative protein folding within the ER and may be involved in retaining proteins.