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UGT1A1 抗体

UGT1A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5708492
发货至: 中国
  • 抗原 See all UGT1A1 抗体
    UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
    适用
    • 46
    • 14
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 2
    • 1
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 20
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This UGT1A1 antibody is un-conjugated
    应用范围
    • 28
    • 22
    • 20
    • 18
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity purified
    免疫原
    A recombinant human partial protein corresponding to amino acids E316-H533 was used as the immunogen for the UGT1A1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product UGT1A1 Primary Antibody
  • 应用备注
    Optimal dilution of the UGT1A1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the UGT1A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
    别名
    UGT1A1 (UGT1A1 产品)
    别名
    BILIQTL1 antibody, GNT1 antibody, HUG-BR1 antibody, UDPGT antibody, UDPGT 1-1 antibody, UGT1 antibody, UGT1A antibody, Gnt1 antibody, UGT1A01 antibody, Udpgt-1a antibody, UgtBr1 antibody, Udpgt antibody, Ugt1 antibody, zgc:123097 antibody, UDP glucuronosyltransferase family 1 member A1 antibody, UDP glucuronosyltransferase 1 family, polypeptide A1 antibody, UDP-glucuronosyltransferase 1-1 antibody, UDP-glucuronosyltransferase antibody, UDP-glucuronosyltransferase 1-6 antibody, UDP glucuronosyltransferase 1 family polypeptide a1 antibody, UGT1A1 antibody, Ugt1a1 antibody, LOC100065342 antibody, LOC100125517 antibody, LOC100229734 antibody, LOC100405984 antibody, LOC100511479 antibody, ugt1a1 antibody
    背景
    UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.
    UniProt
    P22309
    途径
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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