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GFI1 抗体

GFI1 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5708405
发货至: 中国
  • 抗原 See all GFI1 抗体
    GFI1 (Growth Factor Independent 1 (GFI1))
    适用
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    宿主
    • 17
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    克隆类型
    • 19
    • 4
    多克隆
    标记
    • 16
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    This GFI1 antibody is un-conjugated
    应用范围
    • 15
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    • 1
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids NLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRETQH were used as the immunogen for the GFI1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product GFI1 Primary Antibody
  • 应用备注
    Optimal dilution of the GFI1 antibody should be determined by the researcher.\. IHC (FFPE): 1-2 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the GFI1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    GFI1 (Growth Factor Independent 1 (GFI1))
    别名
    GFI1 (GFI1 产品)
    别名
    AW495828 antibody, Gfi-1 antibody, Pal-1 antibody, Pal1 antibody, GFI1 antibody, GFI-1 antibody, GFI1A antibody, SCN2 antibody, ZNF163 antibody, growth factor independent 1 antibody, growth factor independent 1 transcriptional repressor antibody, Gfi1 antibody, GFI1 antibody
    背景
    Zinc finger protein Gfi-1 is a protein that in humans is encoded by the GFI1 gene. This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
    UniProt
    Q99684
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