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ORAI1 抗体

Rockland 100-401-p17 ORAI1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN5706864
Supplier Product No.: 100-401-p17
发货至: 中国
  • 抗原 See all ORAI1 抗体
    ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
    适用
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    克隆类型
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    多克隆
    标记
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    This ORAI1 antibody is un-conjugated
    应用范围
    • 40
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    Western Blotting (WB), ELISA
    Supplier Product No.
    100-401-p17
    Supplier
    Rockland
    原理
    ORAI1 Antibody
    交叉反应 (详细)
    Anti-ORAI-1 antibody is directed against the human ORAI-1.
    产品特性
    Synonyms: rabbit anti-ORAI-1 Antibody, Calcium release-activated calcium channel protein 1, orai-1, Transmembrane protein 142A, ORAI1, CRACM1, TMEM142A
    纯化方法
    The product was prepared from monospecific antiserum by delipidation and defibrination.
    过滤
    Sterile filtered
    免疫原

    Immunogen: This whole rabbit serum was prepared by repeated immunizations with a recombinant fusion protein.

    Immunogen Type: Recombinant Protein

    亚型
    IgG
    Top Product
    Discover our top product ORAI1 Primary Antibody
  • 应用备注

    Application Note: Anti-ORAI-1 has been tested for use in western blotting. Specific conditions for reactivity should be optimized by the end user. Expect bands approximately 32.7 kDa by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1.0 μg/mL

    ELISA Dilution: 1.0 μg/well

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
    别名
    ORAI1 (ORAI1 产品)
    背景
    Background: The ORAI-1 gene codes for the calcium release-activated calcium (CRAC) channel subunit in humans. The CRAC channel subunit mediates calcium influx when activated by the calcium sensor, STIM1, following depletion of intracellular calcium stores. CRAC channels are the primary pathway for calcium influx in T-cells and promote the immune response to pathogens through activation of the transcription factor NFAT. Defects in this gene can be a cause of immune dysfunction due to inactivation of T-cells.
    基因ID
    84876
    NCBI登录号
    NP_116179
    UniProt
    Q96D31
    途径
    TCR Signaling, BCR Signaling
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