MAPKBP1 抗体
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- 抗原 See all MAPKBP1 抗体
- MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAPKBP1 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 免疫原
- mitogen-activated protein kinase binding protein 1
- 亚型
- IgG
- Top Product
- Discover our top product MAPKBP1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05000(MAPKBP1 antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
- 别名
- MAPKBP1 (MAPKBP1 产品)
- 别名
- MGC83682 antibody, JNKBP-1 antibody, 2810483F24Rik antibody, AW123212 antibody, Jnkbp1 antibody, mKIAA0596 antibody, mitogen-activated protein kinase binding protein 1 L homeolog antibody, mitogen-activated protein kinase binding protein 1 antibody, mitogen activated protein kinase binding protein 1 antibody, mapkbp1.L antibody, MAPKBP1 antibody, Mapkbp1 antibody
- 背景
- Synonyms:JNKBP1, KIAA0596 Background:MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1, 514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
- 分子量
- 200-230 kDa
- 基因ID
- 23005
- UniProt
- O60336
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