TIMELESS 抗体
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- 抗原 See all TIMELESS 抗体
- TIMELESS (Timeless Homolog (TIMELESS))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIMELESS antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 免疫原
- timeless homolog (Drosophila)
- 亚型
- IgG
- Top Product
- Discover our top product TIMELESS Primary Antibody
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anti-Timeless Homolog (TIMELESS) (AA 1-1208) antibody
TIMELESS 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1004-1131) antibodyTIMELESS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1-1208) antibodyTIMELESS 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 290-339) antibodyTIMELESS 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, Pig, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人, 小鼠, 大鼠, 犬, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 绵羊, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1109-1207) antibodyTIMELESS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) antibodyTIMELESS 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (C-Term) antibodyTIMELESS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB : 1:500-1:5000 IP : 1:500-1:5000 IHC : 1:20-1:200
- 说明
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A549 cells were subjected to SDS PAGE followed by western blot with FNab08694(TIMELESS antibody) at dilution of 1:1000
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- TIMELESS (Timeless Homolog (TIMELESS))
- 别名
- TIMELESS (TIMELESS 产品)
- 背景
- Synonyms:FLJ12640, FLJ20714, hTIM, Protein timeless homolog, TIM, TIM1, TIMELESS, timeless homolog(Drosophila), TIMELESS1 Background:Plays an important role in the control of DNA replication, maintenance of replication fork stability, maintenance of genome stability throughout normal DNA replication and in the regulation of the circadian clock. Involved in the determination of period length and in the DNA damage-dependent phase advancing of the circadian clock. Negatively regulates CLOCK|NPAS2-ARTNL/BMAL1|ARTNL2/BMAL2-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Forms a complex with TIPIN and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. Timeless promotes TIPIN nuclear localization. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.
- 分子量
- 140 kDa
- 基因ID
- 8914
- UniProt
- Q9UNS1
- 途径
- Protein targeting to Nucleus, Photoperiodism
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