IFIT1 抗体
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- 抗原 See all IFIT1 抗体
- IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IFIT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- interferon-induced protein with tetratricopeptide repeats 1
- 亚型
- IgG
- Top Product
- Discover our top product IFIT1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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U-937 cells were subjected to SDS PAGE followed by western blot with FNab04135( IFIT1 Antibody) at dilution of 1:600
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))
- 别名
- IFIT1 (IFIT1 产品)
- 别名
- C56 antibody, G10P1 antibody, IFI-56 antibody, IFI-56K antibody, IFI56 antibody, IFIT-1 antibody, IFNAI1 antibody, ISG56 antibody, P56 antibody, RNM561 antibody, Ifi56 antibody, Garg16 antibody, DKFZp469C2331 antibody, interferon induced protein with tetratricopeptide repeats 1 antibody, interferon-induced protein with tetratricopeptide repeats 1 antibody, IFIT1 antibody, Ifit1 antibody, LOC488947 antibody, ifit1 antibody, LOC100058990 antibody, LOC100139670 antibody, LOC100475782 antibody
- 背景
- Synonyms:G10P1, GARG 16, IFI 56, IFI 56K, IFI56, IFIT 1, IFIT1, IFNAI1, ISG56, RNM561 Background:Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group(PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
- 分子量
- 55 Kda
- 基因ID
- 3434
- UniProt
- P09914
- 途径
- Hepatitis C
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