WTAP 抗体
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- 抗原 See all WTAP 抗体
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WTAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- 免疫原
- Wilms tumor 1 associated protein
- 亚型
- IgG
- Top Product
- Discover our top product WTAP Primary Antibody
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- 应用备注
- WB:1:500-1:2000
- 说明
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09529(WTAP antibody) at dilution of 1:1000
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
- 别名
- WTAP (WTAP 产品)
- 别名
- MGC75954 antibody, WTAP antibody, RGD1563824 antibody, wu:fi29a09 antibody, zgc:66202 antibody, 2810408K05Rik antibody, 9430038B09Rik antibody, WT1 associated protein antibody, Wilms tumor 1 associated protein antibody, wilms tumor 1 associated protein antibody, WT1 associated protein L homeolog antibody, Wilms tumour 1-associating protein antibody, wtap antibody, WTAP antibody, CpipJ_CPIJ006489 antibody, Wtap antibody, wtap.L antibody
- 背景
- Synonyms:DKFZp686F20131, Female lethal(2)D homolog, hFL(2)D, KIAA0105, WT1 associated protein, WTAP Background:Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724).
- 分子量
- 49kDa,Observed 55kDa
- 基因ID
- 9589
- UniProt
- Q15007
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