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alpha Actinin 抗体

ACTN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5697056
发货至: 中国
  • 抗原 See all alpha Actinin (ACTN) 抗体
    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
    适用
    • 10
    • 8
    • 8
    • 4
    • 1
    人, 小鼠, 大鼠
    宿主
    • 9
    • 2
    克隆类型
    • 9
    • 2
    多克隆
    标记
    • 7
    • 2
    • 2
    This alpha Actinin antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    免疫原
    actinin, alpha 1
    亚型
    IgG
    Top Product
    Discover our top product ACTN Primary Antibody
  • 应用备注
    WB : 1:1000-1:10000 IHC : 1:50-1:500 IF : 1:50-1:500
    说明

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab00322( a-Actinin Antibody) at dilution of 1:2000

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
    别名
    alpha Actinin (ACTN 产品)
    别名
    actinin, alpha 4 antibody, alpha-actinin antibody, ACTN4 antibody, ain1 antibody
    背景
    Synonyms:actinin, alpha 1, ACTN1, alpha Actinin, Alpha actinin 1, F actin cross linking protein, Non muscle alpha actinin 1 Background:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
    分子量
    103 kDa
    UniProt
    P12814
    途径
    Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
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