zgc:158860 antibody, UNQ501 antibody, RGD1563250 antibody, transmembrane protein 205 antibody, Transmembrane protein 205 antibody, transmembrane protein 205 L homeolog antibody, TMEM205 antibody, tmem205 antibody, tm205 antibody, Tmem205 antibody, tmem205.L antibody
背景
TMEM205 is a 189 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2 % of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and Insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene Bcl-3.Synonyms: Transmembrane protein 205