Sacsin 抗体 (AA 3709-3909)
-
- 抗原 See all Sacsin (SACS) 抗体
- Sacsin (SACS) (Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS))
-
抗原表位
- AA 3709-3909
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Sacsin antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
- 品牌
- Picoband™
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for Sacsin detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- 免疫原
- E. coli-derived human Sacsin recombinant protein (Position: E3709-L3909).
- Top Product
- Discover our top product SACS Primary Antibody
-
anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) (AA 983-1150) antibody
SACS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS) antibodySACS 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- Sacsin (SACS) (Spastic Ataxia of Charlevoix-Saguenay (Sacsin) (SACS))
- 别名
- SACS (SACS 产品)
- 别名
- A230052M14 antibody, DNAJC29 antibody, E130115J16Rik antibody, mKIAA0730 antibody, ARSACS antibody, sacsin antibody, sacsin molecular chaperone antibody, Sacs antibody, SACS antibody
- 背景
-
Synonyms: Sacsin, DnaJ homolog subfamily C member 29, DNAJC29, SACS, KIAA0730
Tissue Specificity: Highly expressed in the central nervous system. Also found in skeletal muscle and at low levels in pancreas.
Background: Sacsin also known as DnaJ homolog subfamily C member 29 (DNAJC29) is a protein that in humans is encoded by the SACS gene. This gene consists of nine exons including a gigantic exon spanning more than 12.8k bp. It encodes the sacsin protein, which includes a UBQ region at the N-terminus, a HEPN domain at the C-terminus and a DnaJ region upstream of the HEPN domain. This modular protein is essential for normal mitochondrial network organization. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticityand peripheral neuropathy.
-
