SCRIB 抗体 (AA 172-409)
-
- 抗原 See all SCRIB 抗体
- SCRIB (Scribbled Homolog (SCRIB))
-
抗原表位
- AA 172-409
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SCRIB antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 品牌
- Picoband™
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for SCRIBBLE detection. Tested with WB, IHC-F, ICC, FCM, Direct ELISA in Human,Mouse,Rat.
- 免疫原
- E. coli-derived human SCRIBBLE recombinant protein (Position: F172-K409).
- Top Product
- Discover our top product SCRIB Primary Antibody
-
anti-Scribbled Homolog (SCRIB) antibody
SCRIB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Scribbled Homolog (SCRIB) (AA 382-410), (N-Term) antibodySCRIB 适用: 人 WB 宿主: 兔 Polyclonal RB39490 unconjugated
-
- 应用备注
-
Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.
Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry, 1-3 μg/1x106 cells
Direct ELISA, 0.1-0.5 μg/mL - 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- SCRIB (Scribbled Homolog (SCRIB))
- 别名
- SCRIB (SCRIB 产品)
- 别名
- 0424/05 antibody, CG31082 antibody, CG42614 antibody, CG43398 antibody, CG5462 antibody, CG5467 antibody, CT17324 antibody, Dmel\\CG43398 antibody, Dmel_CG31082 antibody, Dmel_CG42614 antibody, Dmel_CG5462 antibody, Dmel_CG5467 antibody, MENE (3R)-F antibody, SCR antibody, Scb antibody, Scrb antibody, Scrib antibody, ird antibody, ird15 antibody, l(3)673 antibody, l(3)S042405 antibody, l(3)c00119 antibody, l(3)j7B3 antibody, scrb antibody, smi97B antibody, vart antibody, AI118201 antibody, CRIB antibody, Crc antibody, SCRIB1 antibody, Scrb1 antibody, mKIAA0147 antibody, vartul antibody, scrb1 antibody, scribble antibody, scribble1 antibody, si:ch211-12p8.1 antibody, si:zc12p8.1 antibody, CRIB1 antibody, SCRB1 antibody, Vartul antibody, scribbled antibody, scribbled planar cell polarity antibody, scribbled planar cell polarity protein antibody, scrib antibody, Scrib antibody, SCRIB antibody
- 背景
-
Synonyms: Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Tissue Specificity: Expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells (at protein level).
Background: SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. In Drosophila melanogaster, SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis. Deficiency in SCRIB impairs many aspects of cell polarity and cell movement. SCRIB is also likely involved in establishing apical-basal polarity as well as progression from the G1 phase to S phase in the cell cycle as a result of its relationship with cell proliferation and exocytosis.
- UniProt
- Q14160
- 途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
-
