-
- 抗原 See all CCR4 抗体
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CCR4 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 品牌
- Picoband™
- 序列
- LVELEVLQDC TFERYLDYAI QATETLAFVH
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for CCR4 detection. Tested with WB in Human,Mouse,Rat.
- 免疫原
- A synthetic peptide corresponding to a sequence of human CCR4 (LVELEVLQDCTFERYLDYAIQATETLAFVH).
- Top Product
- Discover our top product CCR4 Primary Antibody
-
-
- 应用备注
-
Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot,0.1-0.5 μg/mL
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
-
-
GEC-derived SFRP5 inhibits Wnt5a-induced macrophage chemotaxis and activation." in: PLoS ONE, Vol. 9, Issue 1, pp. e85058, (2014) (PubMed).
: "
-
GEC-derived SFRP5 inhibits Wnt5a-induced macrophage chemotaxis and activation." in: PLoS ONE, Vol. 9, Issue 1, pp. e85058, (2014) (PubMed).
-
- 抗原
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- 别名
- CCR4 (CCR4 产品)
- 别名
- CC-CKR-4 antibody, CD194 antibody, CKR4 antibody, CMKBR4 antibody, ChemR13 antibody, HGCN:14099 antibody, K5-5 antibody, Ccr4 antibody, C-C CKR-4 antibody, CHEMR1 antibody, Cmkbr4 antibody, LESTR antibody, Sdf1r antibody, C-C motif chemokine receptor 4 antibody, chemokine (C-C motif) receptor 4 antibody, CCR4 antibody, Ccr4 antibody
- 背景
-
Synonyms: C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CCR4, K5-5, CD194, CCR4, CMKBR4
Tissue Specificity: Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets, at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expressing the cutaneous lymphocyte antigen (CLA). Expressed in brain microvascular and coronary artery endothelial cells.
Background: CCR4, C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194 (cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
- UniProt
- P51679
-