MYLK 抗体 (AA 1441-1709)
-
- 抗原 See all MYLK 抗体
- MYLK (Myosin Light Chain Kinase (MYLK))
-
抗原表位
- AA 1441-1709
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MYLK antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 品牌
- Picoband™
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for MYLK detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- 免疫原
- E. coli-derived human MYLK recombinant protein (Position: D1441-D1709).
- Top Product
- Discover our top product MYLK Primary Antibody
-
-
- 应用备注
-
Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- MYLK (Myosin Light Chain Kinase (MYLK))
- 别名
- MYLK (MYLK 产品)
- 别名
- AAT7 antibody, KRP antibody, MLCK antibody, MLCK1 antibody, MLCK108 antibody, MLCK210 antibody, MSTP083 antibody, MYLK1 antibody, smMLCK antibody, 9530072E15Rik antibody, A930019C19Rik antibody, AW489456 antibody, Mlck antibody, SMMLCK antibody, mlck antibody, fj60a06 antibody, mlck1a antibody, mylk antibody, wu:fj60a06 antibody, zmlck1 antibody, myosin light chain kinase antibody, myosin, light polypeptide kinase antibody, myosin, light chain kinase a antibody, MYLK antibody, Mylk antibody, mylka antibody
- 背景
-
Synonyms: Myosin light chain kinase, smooth muscle, MLCK, s mMLCK, Kinase-related protein, KRP, Telokin, Myosin light chain kinase, smooth muscle, deglutamylated form, MYLK, MLCK, MLCK1, MYLK1
Tissue Specificity: Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific. Non-muscle isoform 2 is the dominant splice variant expressed in various tissues. Telokin has been found in a wide variety of adult and fetal tissues. Accumulates in well differentiated enterocytes of the intestinal epithelium in response to tumor necrosis factor (TNF).
Background: Myosin light chain kinase, smooth muscle also known as kinase-related protein (KRP) or telokin is an enzyme that in humans is encoded by the MYLK gene. This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin.
- UniProt
- Q15746
-