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Phospholipase C gamma 2 抗体 (AA 1201-1258)

PLCG2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5692854
发货至: 中国
  • 抗原 See all Phospholipase C gamma 2 (PLCG2) 抗体
    Phospholipase C gamma 2 (PLCG2)
    抗原表位
    • 29
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    AA 1201-1258
    适用
    • 124
    • 67
    • 53
    • 6
    • 4
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    • 1
    人, 大鼠, 小鼠
    宿主
    • 118
    • 6
    克隆类型
    • 119
    • 5
    多克隆
    标记
    • 56
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    This Phospholipase C gamma 2 antibody is un-conjugated
    应用范围
    • 94
    • 40
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    • 31
    • 21
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    • 11
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for PLCG 2 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
    免疫原
    E. coli-derived human PLCG 2 recombinant protein (Position: R1201-V1258).
    Top Product
    Discover our top product PLCG2 Primary Antibody
  • 应用备注

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Application Details: Western blot,0.1-0.5 μg/mL
    Immunohistochemistry(Paraffin-embedded Section),0.5-1 μg/mL
    Direct ELISA,0.1-0.5 μg/mL

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Phospholipase C gamma 2 (PLCG2)
    别名
    PLCG2 (PLCG2 产品)
    别名
    PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
    背景

    Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, PLC-IV, Phospholipase C-gamma-2, PLC-gamma-2, PLCG2

    Background: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene. The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

    UniProt
    P16885
    途径
    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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