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ICAM-3/CD50 抗体 (Domain 1, Domain 2)

ICAM3 适用: 人 WB, FACS, ELISA, IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal JA4 unconjugated
产品编号 ABIN5691103
发货至: 中国
  • 抗原 See all ICAM-3/CD50 (ICAM3) 抗体
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    抗原表位
    • 8
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Domain 1, Domain 2
    适用
    • 110
    • 3
    • 2
    • 2
    宿主
    • 66
    • 43
    • 1
    小鼠
    克隆类型
    • 70
    • 40
    单克隆
    标记
    • 59
    • 10
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM-3/CD50 antibody is un-conjugated
    应用范围
    • 59
    • 47
    • 45
    • 33
    • 26
    • 24
    • 21
    • 12
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    JA4 recognizes a linear epitope in domains 1 and 2 of ICAM-3.
    免疫原
    JA4 is a mouse monoclonal IgG1/k antibody derived by fusion of mouse Ag8.653 cells with spleen cells from a BALB/c mouse immunized with an ICAM-3/HEK transfectant.
    克隆位点
    JA4
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ICAM3 Primary Antibody
  • 应用备注
    JA4 is suitable for immunoblotting, immunocytochemistry, immunohistochemistry on frozen tissues and flow cytometry. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
    限制
    仅限研究用
  • 缓冲液
    Each vial contains 100 μL 1 mg/mL purified monoclonal antibody in PBS containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C, or in small aliquots at -20°C.
  • 抗原
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    别名
    ICAM-3 (ICAM3 产品)
    别名
    CD50 antibody, CDW50 antibody, ICAM-R antibody, ICAM-3 antibody, ICAM3 antibody, intercellular adhesion molecule 3 antibody, ICAM3 antibody, Icam3 antibody
    背景
    Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a type I transmembrane glycoprotein, which normally contain 2-9 immunoglobulin-like C2-type domains, and binds to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined.
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