TRIP12 抗体 (AA 1930-1980)
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- 抗原 See all TRIP12 抗体
- TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))
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抗原表位
- AA 1930-1980
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIP12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- TRIP12 antibody is human, mouse and rat reactive. At least four isoforms are known to exist.
- 纯化方法
- TRIP12 antibody is affinity chromatography purified via peptide column.
- 免疫原
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TRIP12 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human TRIP12.
The immunogen is located within amino acids 1930 - 1980 of TRIP12. - 亚型
- IgG
- Top Product
- Discover our top product TRIP12 Primary Antibody
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anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 1-240) antibody
TRIP12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 1-240) antibodyTRIP12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 991-1023) antibodyTRIP12 适用: 人 WB 宿主: 兔 Polyclonal RB54123 unconjugated
anti-Thyroid Hormone Receptor Interactor 12 (TRIP12) (AA 75-125) antibodyTRIP12 适用: 人, 犬, 豚鼠, Pig WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- TRIP12 antibody can be used for detection of TRIP12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TRIP12 antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- TRIP12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))
- 别名
- TRIP12 (TRIP12 产品)
- 别名
- ULF antibody, TRIP-12 antibody, 1110036I07Rik antibody, 6720416K24Rik antibody, AA410158 antibody, Gtl6 antibody, thyroid hormone receptor interactor 12 antibody, E3 ubiquitin-protein ligase TRIP12 antibody, TRIP12 antibody, CpipJ_CPIJ012812 antibody, PTRG_06487 antibody, LOAG_11488 antibody, LOC100631469 antibody, Trip12 antibody
- 背景
- Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner (1). TRIP12 (thyroid hormone receptor interactor 12) is an ATP-dependent E3 ubiquitin ligase involved in the human ubiquitin fusion degradation (UFD) pathway and also modulates the NEDD8 pathway (2,3). TRIP12 contains one WWE domain and a single HECT (E6AP-type E3 ubiquitin-protein ligase) domain suggested to contain a noncovalent ubiquitin-binding site (4). TRIP12 acts as a key regulator of DNA damage response and the ubiquitin ligase activity of TRIP12 is essential for mouse development (5).
- 分子量
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Predicted: 219 kDa
Observed: 220 kDa - 基因ID
- 9320
- NCBI登录号
- NP_004229
- UniProt
- Q14669
- 途径
- Nuclear Hormone Receptor Binding
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