Synaptophysin 2 抗体 (AA 257-261)
适用: 大鼠
WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all Synaptophysin 2 products
- Synaptophysin 2
- 抗原表位
- AA 257-261
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Synaptophysin 2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of total synaptophysin 2 protein.
- 纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- synaptophysin 2 antibody was raised against a peptide sequence around aa.257~261 (G-P-T-S-F) derived from Rat synaptophysin 2.
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anti-Synaptophysin 2 (C-Term) antibody
适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western Blot: 1:500~1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store antibody at -20°C for up to one year.
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- 抗原
- Synaptophysin 2
- Abstract
- Synaptophysin 2 产品
- 别名
- synaptoporin antibody, Synpr antibody
- 背景
- Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).
- 分子量
- 37 kDa
- 基因ID
- 66030
- NCBI登录号
- NP_076464
- UniProt
- P22831
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