TWIST2 抗体 (AA 26-30)
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北京 101111
Quick Overview for TWIST2 抗体 (AA 26-30) (ABIN5689370)
抗原
See all TWIST2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-30
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特异性
- This antibody detects endogenous level of total Twist2 protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- Twist2 antibody was raised against a peptide sequence around aa.26~30 (P-K-R-F-G) derived from Human Twist2.
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- TWIST2 (Twist Homolog 2 (TWIST2))
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别名
- Twist2
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背景
- Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
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分子量
- 18 kDa
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基因ID
- 117581
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NCBI登录号
- NP_476527
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UniProt
- Q8WVJ9
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途径
- Chromatin Binding
抗原
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