Connexin 抗体 (C-Term)
适用: 绵羊, 非洲爪蟾, 斑马鱼, 小鸡, 犬, 人, 小鼠, 大鼠
WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all Connexin products
- Connexin
- 抗原表位
- C-Term
- 适用
- 绵羊, 非洲爪蟾, 斑马鱼, 小鸡, 犬, 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity Purified
- 免疫原
- Peptide corresponding to amino acid residues from the C-terminal region of rat connexin43.
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- 应用备注
- The antibody has been directly tested for reactivity in Western blots in rat tissues. It is anticipated that the antibody will also work with chicken, dog, finch, human, mouse, non-human primate, sheep, Xenopus and zebra fish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
- 储存条件
- -20 °C
- 储存方法
- Connexin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- 抗原
- Connexin
- Abstract
- Connexin 产品
- 别名
- connexin antibody, LOC100128922 antibody
- 背景
- Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002, Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b).
- 分子量
- 43 kDa
- 基因ID
- 24392
- UniProt
- P08050
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