LAIR1 抗体 (AA 22-165)
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- 抗原 See all LAIR1 抗体
- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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抗原表位
- AA 22-165
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LAIR1 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- CD305 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD305 (AA: 22-165) expressed in E. Coli.
- 克隆位点
- 1G8B6
- 亚型
- IgG1
- Top Product
- Discover our top product LAIR1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
- 别名
- CD305 (LAIR1 产品)
- 别名
- 5133400O11Rik antibody, BB115266 antibody, D7Bwg0421e antibody, Lair-1 antibody, mLair-1 antibody, CD305 antibody, LAIR-1 antibody, leukocyte-associated Ig-like receptor 1 antibody, leukocyte associated immunoglobulin like receptor 1 antibody, leukocyte-associated immunoglobulin-like receptor 1 antibody, Lair1 antibody, LAIR1 antibody
- 背景
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Description: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
Aliases: LAIR1, LAIR-1
- 分子量
- 31.4kDa
- 基因ID
- 3903
- HGNC
- 967
- UniProt
- Q6GTX8
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