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CD42b 抗体 (AA 17-183)

GP1BA 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6H6B11 unconjugated
产品编号 ABIN5684108
发货至: 中国
  • 抗原 See all CD42b (GP1BA) 抗体
    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
    抗原表位
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 17-183
    适用
    • 67
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    • 31
    • 2
    小鼠
    克隆类型
    • 39
    • 30
    单克隆
    标记
    • 40
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CD42b antibody is un-conjugated
    应用范围
    • 32
    • 29
    • 19
    • 12
    • 10
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA
    原理
    CD42B Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CD42B (AA: 17-183) expressed in E. Coli.
    克隆位点
    6H6B11
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
    别名
    CD42B (GP1BA 产品)
    别名
    BDPLT1 antibody, BDPLT3 antibody, BSS antibody, CD42B antibody, CD42b-alpha antibody, DBPLT3 antibody, GP1B antibody, GPIbA antibody, VWDP antibody, GP1BA antibody, GPIba antibody, GPIbalpha antibody, glycoprotein Ib platelet alpha subunit antibody, glycoprotein Ib (platelet), alpha polypeptide antibody, glycoprotein 1b, alpha polypeptide antibody, GP1BA antibody, Gp1ba antibody
    背景

    Description: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

    Aliases: GP1BA, BSS, GP1B, VWDP, GPIbA, BDPLT1, BDPLT3, DBPLT3, GPIbalpha, CD42b-alpha

    分子量
    71.5kDa
    基因ID
    2811
    HGNC
    2811
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