Ancient Ubiquitous Protein 1 抗体 (AA 229-410)
Quick Overview for Ancient Ubiquitous Protein 1 抗体 (AA 229-410) (ABIN5684097)
抗原
See all Ancient Ubiquitous Protein 1 (Aup1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 229-410
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原理
- AUP1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human AUP1 (AA: 229-410) expressed in E. Coli.
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亚型
- IgG2b
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anti-Ancient Ubiquitous Protein 1 (Aup1) antibody
Aup1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ancient Ubiquitous Protein 1 (Aup1) (AA 201-410) antibodyAup1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ancient Ubiquitous Protein 1 (Aup1) antibodyAup1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ancient Ubiquitous Protein 1 (Aup1) (AA 201-410) antibodyAup1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Ancient Ubiquitous Protein 1 (Aup1)
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别名
- AUP1
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背景
- The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.
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分子量
- 53 kDa
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UniProt
- Q9Y679
抗原
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