TIM3 抗体 (AA 224-301)
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- 抗原 See all TIM3 (TIM 3) 抗体
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
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抗原表位
- AA 224-301
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TIM3 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA
- 原理
- TIM3 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human TIM3 (AA: 224-301) expressed in E. Coli.
- 克隆位点
- 2A7A6
- 亚型
- IgG1
- Top Product
- Discover our top product TIM 3 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 别名
- TIM3 (TIM 3 产品)
- 别名
- HAVCR2 antibody, MGC140131 antibody, HAVcr-2 antibody, KIM-3 antibody, TIM3 antibody, TIMD-3 antibody, TIMD3 antibody, Tim-3 antibody, TIM-3 antibody, Tim3 antibody, Timd3 antibody, tim3 antibody, hepatitis A virus cellular receptor 2 antibody, HAVCR2 antibody, Havcr2 antibody
- 背景
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Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Aliases: HAVCR2, CD366, KIM-3, TIMD3, Tim-3, TIMD-3, HAVcr-2
- 分子量
- 33.4kDa
- 基因ID
- 84868
- HGNC
- 550
- UniProt
- Q8TDQ0
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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