TXNIP 抗体
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- 抗原 See all TXNIP 抗体
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TXNIP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody reacts with Txnip/VDUP1 (50 kDa) on Western blotting and Immunoprecipitation.
- 纯化方法
- Protein-A Agarose Chromatography of hybridoma supernatant.
- 免疫原
- Human recombinant VDUP-1/Txnip.
- 克隆位点
- JY2
- 亚型
- IgG1
- Top Product
- Discover our top product TXNIP Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
- 别名
- TXNIP / VDUP1 (TXNIP 产品)
- 背景
- Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX. It has been reported that Txnip plays important roles in diverse cellular processes, including the regulation of cellular redox balance, apoptosis, proliferation, and differentiation.Synonyms: Thioredoxin-binding protein 2, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1
- 基因ID
- 10628
- NCBI登录号
- NP_006463
- UniProt
- Q9H3M7
- 途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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