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MAD2L1 抗体

MAD2L1 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 小鼠 Monoclonal 2G9 unconjugated
产品编号 ABIN567786
发货至: 中国
  • 抗原 See all MAD2L1 抗体
    MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))
    适用
    • 68
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    人, 小鼠, 大鼠
    宿主
    • 57
    • 10
    • 1
    • 1
    小鼠
    克隆类型
    • 52
    • 17
    单克隆
    标记
    • 38
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    • 2
    • 1
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    This MAD2L1 antibody is un-conjugated
    应用范围
    • 32
    • 22
    • 14
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    • 11
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    • 1
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    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    This antibody reacts with MAD2 (25 kDa) on Western blotting and Immunoprecipitation.
    纯化方法
    Protein-A Agarose Chromatography of hybridoma supernatant.
    免疫原
    Recombinant Human MAD2.
    克隆位点
    2G9
    亚型
    IgG1
    Top Product
    Discover our top product MAD2L1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 50 % Glycerol without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))
    别名
    MAD2L1 (MAD2L1 产品)
    背景
    Some of the spindle checkpoint components are evolutionarily conserved from yeast to human. They include mitotic arrest deficiency 1 (MAD1), MAD2, MAD3/BUBR1, budding uninhibited by benomyl 1 (BUB1), BUB3, and monopolar spindle 1 (MPS1). MAD1 interacts with several checkpoint proteins, forming a complex with MAD2 and recruiting MAD2 to unattached kinetochores. MAD1 and Cdc20 can bind MAD2, but these two bindings are exclusive. They share a 10-residue MAD2-binding motif. It has been suggested that MAD1 acts as a positive regulator and a competitive inhibitor of the MAD2-Cdc20 complex.Synonyms: MAD2, Mitotic spindle assembly checkpoint protein MAD2A
    基因ID
    4085
    NCBI登录号
    NP_002349
    UniProt
    Q13257
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