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Cyclin A 抗体

CCNA2 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 小鼠 Monoclonal E67-1 unconjugated
产品编号 ABIN567779
发货至: 中国
  • 抗原 See all Cyclin A (CCNA2) 抗体
    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 56
    • 33
    • 1
    小鼠
    克隆类型
    • 47
    • 43
    单克隆
    标记
    • 63
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    This Cyclin A antibody is un-conjugated
    应用范围
    • 54
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    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    This antibody reacts with Cyclin A (55 kDa) on Western blotting and Immunoprecipitation.
    纯化方法
    Protein-A Agarose Chromatography of hybridoma supernatant.
    免疫原
    Bovine recombinant Cyclin A.
    克隆位点
    E67-1
    亚型
    IgG2a
    Top Product
    Discover our top product CCNA2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 50 % Glycerol without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
    别名
    Cyclin A2 (CCNA2 产品)
    背景
    Cyclin A is a 60 kDa cyclin that binds both cdk2 and p34cdc2 (cdk1), giving two distinct cyclin A kinase activities, one appearing in G1/S phase, the other in G2/M. The level of cyclin A protein peaks in S-phase, and the activity of the cdk2-cyclin A complexes is essential for DNA replication and progression through S phase. Cyclin A is thus a marker for actively proliferating cells and for cells in S-phase. In normal cells, cdk2-cyclin A complexes associate with PCNA and p21CIPP1/WAF1. In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcrIPPtion factors DRT F1 and E2F, and retinoblastoma protein, p110.Synonyms: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2
    基因ID
    890
    NCBI登录号
    NP_001228
    UniProt
    P20248
    途径
    PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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