ERO1LB 抗体 (AA 1-100) (Biotin)
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- 抗原 See all ERO1LB 抗体
- ERO1LB (ERO1-Like beta (ERO1LB))
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抗原表位
- AA 1-100
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ERO1LB antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Pig,Rabbit,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ERO1LB
- 亚型
- IgG
- Top Product
- Discover our top product ERO1LB Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ERO1LB (ERO1-Like beta (ERO1LB))
- 别名
- ERO1LB (ERO1LB 产品)
- 别名
- RGD1563548 antibody, 1300013B24Rik antibody, 1700065B09Rik antibody, AI447560 antibody, ero1-beta antibody, endoplasmic reticulum oxidoreductase 1 beta antibody, ERO1-like beta (S. cerevisiae) antibody, Ero1b antibody, ERO1B antibody, Ero1lb antibody
- 背景
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Synonyms: Endoplasmic oxidoreductin-1-like protein B, ERO1-L-beta, ERO1B, ERO1-like protein beta, Oxidoreductin-1-L-beta
Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.
- 基因ID
- 56605
- UniProt
- Q86YB8
- 途径
- SARS-CoV-2 Protein Interactome
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