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HTR2A 抗体 (AA 171-270)

HTR2A 适用: 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5675437
发货至: 中国
  • 抗原 See all HTR2A 抗体
    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
    抗原表位
    • 16
    • 15
    • 7
    • 5
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    • 4
    • 2
    • 2
    • 1
    • 1
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    AA 171-270
    适用
    • 67
    • 53
    • 50
    • 7
    • 5
    • 3
    • 1
    • 1
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    小鼠, 大鼠
    宿主
    • 71
    • 1
    克隆类型
    • 72
    多克隆
    标记
    • 21
    • 5
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This HTR2A antibody is un-conjugated
    应用范围
    • 52
    • 27
    • 26
    • 21
    • 12
    • 10
    • 7
    • 6
    • 5
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human 5HT2A Receptor
    亚型
    IgG
    Top Product
    Discover our top product HTR2A Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
    别名
    5HT2A Receptor (HTR2A 产品)
    别名
    5-HT2A antibody, HTR2 antibody, 5-HT-2 antibody, 5-HT-2A antibody, 5-HTR2A antibody, LOC100009461 antibody, E030013E04 antibody, Htr-2 antibody, Htr2 antibody, 5Ht-2 antibody, 5HT2A antibody, 5HTR2A antibody, HTR2A antibody, Htr2a antibody, 5HT2 antibody, 5-hydroxytryptamine receptor 2A antibody, 5-hydroxytryptamine (serotonin) receptor 2A antibody, HTR2A antibody, Htr2a antibody
    背景

    Synonyms: 5-hydroxytryptamine receptor 2A, HTR2A, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A, HTR2A, HTR2

    Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores (PubMed:18703043, PubMed:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

    基因ID
    8549
    UniProt
    P28223
    途径
    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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