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MED12 抗体 (AA 251-350)

MED12 适用: 小鼠, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5675220
发货至: 中国
  • 抗原 See all MED12 抗体
    MED12 (Mediator Complex Subunit 12 (MED12))
    抗原表位
    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    适用
    • 28
    • 24
    • 16
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 38
    • 1
    • 1
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED12 antibody is un-conjugated
    应用范围
    • 24
    • 14
    • 12
    • 12
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Cow,Sheep,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MED12/Trap230
    亚型
    IgG
    Top Product
    Discover our top product MED12 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MED12 (Mediator Complex Subunit 12 (MED12))
    别名
    MED12/Trap230 (MED12 产品)
    别名
    ARC240 antibody, CAGH45 antibody, FGS1 antibody, HOPA antibody, MED12S antibody, OHDOX antibody, OKS antibody, OPA1 antibody, TNRC11 antibody, TRAP230 antibody, 230kDa antibody, Mopa antibody, OPA-1 antibody, Tnrc11 antibody, Trap230 antibody, mediator complex subunit 12 antibody, MED12 antibody, Med12 antibody, med12 antibody
    背景

    Synonyms: Mediator of RNA polymerase II transcription subunit 12, MED12, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45 Mediator complex subunit 12, OPA-containing protein, Thyroid hormone receptor-associated protein complex 230 kDa component, Trap230, Trinucleotide repeat-containing gene 11 protein, MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230

    Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

    基因ID
    9968
    UniProt
    Q93074
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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