EIF4A3 抗体 (AA 351-411)
-
- 抗原 See all EIF4A3 抗体
- EIF4A3 (Eukaryotic Translation Initiation Factor 4A3 (EIF4A3))
-
抗原表位
- AA 351-411
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This EIF4A3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human eIF4A3
- 亚型
- IgG
- Top Product
- Discover our top product EIF4A3 Primary Antibody
-
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) (AA 6-166) antibody
EIF4A3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) (AA 1-210) antibodyEIF4A3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) (AA 312-411) antibodyEIF4A3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) (AA 136-185) antibodyEIF4A3 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 豚鼠, 马, 小鸡, Pig, 非洲爪蟾, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) (AA 51-100) antibodyEIF4A3 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 豚鼠, 马, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) (AA 1-50) antibodyEIF4A3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig IHC, IP, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) (AA 125-175) antibodyEIF4A3 适用: 人, 小鼠, 大鼠, 斑马鱼, 小鸡, 非洲爪蟾 WB, IHC, IP, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) antibodyEIF4A3 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, C. elegans WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) (N-Term) antibodyEIF4A3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- EIF4A3 (Eukaryotic Translation Initiation Factor 4A3 (EIF4A3))
- 别名
- eIF4A3 (EIF4A3 产品)
- 别名
- DDX48 antibody, NMP265 antibody, NUK34 antibody, eIF4AIII antibody, 2400003O03Rik antibody, Ddx48 antibody, eIF4A-III antibody, mKIAA0111 antibody, ddx48 antibody, nuk34 antibody, nmp265 antibody, eif4aiii antibody, EIF4A3 antibody, eif4a3 antibody, zgc:56139 antibody, XeIF-4AIII antibody, eif4a3-B antibody, eukaryotic translation initiation factor 4A3 antibody, eukaryotic initiation factor 4A-III antibody, eukaryotic translation initiation factor 4A3 S homeolog antibody, Eukaryotic initiation factor 4A-III antibody, EIF4A3 antibody, Eif4a3 antibody, eif4a3 antibody, LOC100185906 antibody, eif4a3.S antibody, if4a3 antibody
- 背景
-
Synonyms: Eukaryotic initiation factor 4A-III, EIF4A3, eIF-4A-III, ATP-dependent RNA helicase DDX48, ATP-dependent RNA helicase eIF4A-3, DEAD box protein 48, Eukaryotic initiation factor 4A-like NUK-34, Eukaryotic translation initiation factor 4A isoform 3, Nuclear matrix protein 265, NMP 265, hNMP 265, Eukaryotic initiation factor 4A-III, N-terminally processed, EIF4A3, DDX48, KIAA0111
Background: ATP-dependent RNA helicase. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). Constitutes at least part of the platform anchoring other EJC proteins to spliced mRNAs. Its RNA-dependent ATPase and RNA-helicase activities are induced by CASC3, but abolished in presence of the MAGOH/RBM8A heterodimer, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation. The inhibition of ATPase activity by the MAGOH/RBM8A heterodimer increases the RNA-binding affinity of the EJC. Involved in translational enhancement of spliced mRNAs after formation of the 80S ribosome complex. Binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions. Shows higher affinity for single-stranded RNA in an ATP-bound core EJC complex than after the ATP is hydrolyzed.
- 基因ID
- 9775
- UniProt
- P38919
-
