ACHB3 抗体 (N-Term)
LOC101456006
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
1 image
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- 抗原 See all ACHB3 (LOC101456006) products
- ACHB3 (LOC101456006) (Neuronal Acetylcholine Receptor Subunit alpha-2 (LOC101456006))
- 抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACHB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QGYQKWVRPV LHSNDTIKVY FGLKISQLVD VDEKNQLMTT NVWLKQEWTD
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against ACHB3. It was validated on Western Blot.
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ACHB3
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ACHB3 (LOC101456006) (Neuronal Acetylcholine Receptor Subunit alpha-2 (LOC101456006))
- 别名
- ACHB3 (LOC101456006 产品)
- 背景
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The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region.
Alias Symbols: CHRNB3,
Protein Size: 458 - 基因ID
- 1142
- NCBI登录号
- NP_000740
- UniProt
- Q05901
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