CERS6 抗体 (AA 62-131)
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- 抗原 See all CERS6 抗体
- CERS6 (Ceramide Synthase 6 (CERS6))
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抗原表位
- AA 62-131
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CERS6 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Mouse monoclonal antibody raised against a partial recombinant LASS6.
- 序列
- PCAIALNIQA NGPQIAPPNA ILEKVFTAIT KHPDEKRLEG LSKQLDWDVR SIQRWFRQRR NQEKPSTLTR
- 交叉反应
- 人
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- LASS6 (NP_982288, 62 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 5H7
- 亚型
- IgG2a
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. ..." in: The Journal of clinical investigation, Vol. 126, Issue 1, pp. 254-65, (2016) (PubMed).
: "Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153009, (2016) (PubMed).
: "Bcl2L13 is a ceramide synthase inhibitor in glioblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 15, pp. 5682-7, (2014) (PubMed).
: "Modulation of ceramide synthase activity via dimerization." in: The Journal of biological chemistry, Vol. 287, Issue 25, pp. 21025-33, (2012) (PubMed).
: "D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein ..." in: Biochimie, Vol. 93, Issue 9, pp. 1446-59, (2011) (PubMed).
: "Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells." in: Cellular signalling, Vol. 22, Issue 9, pp. 1300-7, (2010) (PubMed).
in: (PubMed).
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Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. ..." in: The Journal of clinical investigation, Vol. 126, Issue 1, pp. 254-65, (2016) (PubMed).
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- 抗原
- CERS6 (Ceramide Synthase 6 (CERS6))
- 别名
- LASS6 (CERS6 产品)
- 别名
- si:ch211-278b7.1 antibody, CERS6 antibody, CERS5 antibody, LASS6 antibody, 4732462C07Rik antibody, AW544719 antibody, Lass6 antibody, T1L antibody, RGD1561599 antibody, ceramide synthase 6 antibody, CERS6 antibody, cers6 antibody, Cers6 antibody
- 背景
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Full Gene Name: LAG1 homolog, ceramide synthase 6
Synonyms: CerS6,MGC129949,MGC129950 - 基因ID
- 253782
- NCBI登录号
- NM_203463
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