-
- 抗原 See all CERS6 抗体
- CERS6 (Ceramide Synthase 6 (CERS6))
-
抗原表位
- AA 62-131
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 多克隆
-
标记
- This CERS6 antibody is un-conjugated
-
应用范围
- ELISA, Western Blotting (WB)
- 原理
- Mouse polyclonal antibody raised against a partial recombinant LASS6.
- 序列
- PCAIALNIQA NGPQIAPPNA ILEKVFTAIT KHPDEKRLEG LSKQLDWDVR SIQRWFRQRR NQEKPSTLTR
- 交叉反应
- 人
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- LASS6 (NP_982288, 62 a.a. ~ 131 a.a) partial recombinant protein with GST tag.
- Top Product
- Discover our top product CERS6 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- 50 % glycerol
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
-
Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6." in: Cell death & disease, Vol. 6, pp. e1691, (2015) (PubMed).
: "Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse." in: The Journal of clinical investigation, Vol. 123, Issue 10, pp. 4344-58, (2013) (PubMed).
: "Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells." in: Anticancer research, Vol. 32, Issue 3, pp. 753-60, (2012) (PubMed).
: "siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy." in: Anticancer research, Vol. 32, Issue 7, pp. 2479-85, (2012) (PubMed).
: "Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi ..." in: The Journal of biological chemistry, Vol. 286, Issue 49, pp. 42446-58, (2011) (PubMed).
: "Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 1, pp. 296-308, (2010) (PubMed).
: "Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells." in: Oncogene, Vol. 28, Issue 8, pp. 1132-41, (2009) (PubMed).
: "Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas." in: Molecular cancer therapeutics, Vol. 6, Issue 2, pp. 712-22, (2007) (PubMed).
: "JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction." in: The Journal of biological chemistry, Vol. 282, Issue 35, pp. 25940-9, (2007) (PubMed).
: "
-
Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6." in: Cell death & disease, Vol. 6, pp. e1691, (2015) (PubMed).
-
- 抗原
- CERS6 (Ceramide Synthase 6 (CERS6))
- 别名
- LASS6 (CERS6 产品)
- 别名
- si:ch211-278b7.1 antibody, CERS6 antibody, CERS5 antibody, LASS6 antibody, 4732462C07Rik antibody, AW544719 antibody, Lass6 antibody, T1L antibody, RGD1561599 antibody, ceramide synthase 6 antibody, CERS6 antibody, cers6 antibody, Cers6 antibody
- 背景
-
Full Gene Name: LAG1 homolog, ceramide synthase 6
Synonyms: CerS6,MGC129949,MGC129950 - 基因ID
- 253782
- NCBI登录号
- NM_203463
-