Recombinant CD33 (Gemtuzumab Biosimilar) 抗体
适用: 人
FACS, IF
宿主: 兔
Chimeric
HP67-6
unconjugated
Recombinant Antibody
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- 抗原 See all CD33 (Gemtuzumab Biosimilar) products
- CD33 (Gemtuzumab Biosimilar)
- 抗体类型
- Recombinant Antibody
- 适用
- 人
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宿主
- 兔
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克隆类型
- Chimeric
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标记
- This CD33 (Gemtuzumab Biosimilar) antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 原理
- Anti-CD33 [hP67.6 (Gemtuzumab)], Rabbit IgG, kappa
- 特异性
- Recognises human CD33.
- 产品特性
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Original Species of Ab: Human
Original Format of Ab: IgG4
- 纯化方法
- Protein A affinity purified
- 纯度
- > 98 % as determined by SDS-PAGE
- 内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- 免疫原
- Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
- 克隆位点
- HP67-6
- 亚型
- IgG kappa
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anti-CD33 (Gemtuzumab Biosimilar) antibody
Research Grade 适用: 人 FACS 宿主: Humanized Monoclonal unconjugated Recombinant Antibody
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- 应用备注
- A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
- 说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- 抗原
- CD33 (Gemtuzumab Biosimilar)
- Abstract
- CD33 (Gemtuzumab Biosimilar) 产品
- 物质类
- Biosimilar
- 背景
- Siglec-3
- UniProt
- P20138
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