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Recombinant CD33 (Gemtuzumab Biosimilar) 抗体

适用: 人 FACS, IF 宿主: Human Monoclonal HP67-6 unconjugated Recombinant Antibody
产品编号 ABIN5668210
发货至: 中国
  • 抗原 See all CD33 (Gemtuzumab Biosimilar) products
    CD33 (Gemtuzumab Biosimilar)
    抗体类型
    Recombinant Antibody
    适用
    宿主
    • 1
    • 1
    • 1
    Human
    克隆类型
    • 3
    单克隆
    标记
    • 3
    This CD33 (Gemtuzumab Biosimilar) antibody is un-conjugated
    应用范围
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    Recognises human CD33.
    产品特性

    OriginalSpeciesName: Human

    OriginalFormat: IgG4

    纯化方法
    Purified antibody.
    纯度
    > 98 % as determined by SDS-PAGE
    内毒素水平
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    免疫原
    Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
    克隆位点
    HP67-6
    亚型
    IgG4 kappa
  • 应用备注
    A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    CD33 (Gemtuzumab Biosimilar)
    Abstract
    CD33 (Gemtuzumab Biosimilar) 产品
    别名
    SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, CD33 molecule antibody, CD33 antibody
    物质类
    Biosimilar
    背景
    Siglec-3
    UniProt
    P20138
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