Recombinant ITGA4 (Natalizumab Biosimilar) 抗体
(1 reference)-
- 抗原 See all ITGA4 (Natalizumab Biosimilar) products
- ITGA4 (Natalizumab Biosimilar)
- 抗体类型
- Recombinant Antibody
- 适用
- 人
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宿主
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Human
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克隆类型
- 单克隆
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标记
- This ITGA4 (Natalizumab Biosimilar) antibody is un-conjugated
- 应用范围
- Flow Cytometry (FACS), Blocking Reagent (BR)
- 特异性
- This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
- 产品特性
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OriginalSpeciesName: Human
OriginalFormat: IgG4
- 纯化方法
- Purified antibody.
- 纯度
- > 98 % as determined by SDS-PAGE
- 内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- 免疫原
- The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
- 亚型
- IgG4 kappa
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anti-ITGA4 (Natalizumab Biosimilar) antibody
适用: 人 FACS, BR 宿主: 兔 Chimeric unconjugated Recombinant Antibody
anti-ITGA4 (Natalizumab Biosimilar) antibodyResearch Grade 适用: 人 FACS 宿主: Humanized Monoclonal unconjugated Recombinant Antibody
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- 应用备注
- This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
- 说明
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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-
: "An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family." in: PloS one, Vol. 17, Issue 9, pp. e0274667, (2022) (PubMed).
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: "An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family." in: PloS one, Vol. 17, Issue 9, pp. e0274667, (2022) (PubMed).
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- 抗原
- ITGA4 (Natalizumab Biosimilar)
- Abstract
- ITGA4 (Natalizumab Biosimilar) 产品
- 别名
- CD49D antibody, IA4 antibody, integrin subunit alpha 4 antibody, ITGA4 antibody
- 背景
- CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV
- UniProt
- P13612
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