Recombinant TNF alpha (Adalimumab Biosimilar) 抗体
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- 抗原 See all TNF alpha (Adalimumab Biosimilar) products
- TNF alpha (Adalimumab Biosimilar)
- 抗体类型
- Recombinant Antibody
- 适用
- 人
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宿主
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Human
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克隆类型
- 单克隆
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标记
- This TNF alpha (Adalimumab Biosimilar) antibody is un-conjugated
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应用范围
- ELISA, Blocking Reagent (BR), Immunofluorescence (IF), Immunohistochemistry (IHC)
- 特异性
- Binds to soluble TNF-alpha, but not to lymphotoxin (TNF beta).
- 产品特性
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OriginalSpeciesName: Human
OriginalFormat: IgG1
- 纯化方法
- Purified antibody.
- 纯度
- > 98 % as determined by SDS-PAGE
- 内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- 免疫原
- This antibody was generated by affinity maturation from the 2SD4 scFv, which in turn was selected on human TNF alpha by guided phage-display technology, using the murine anti-hTNF alpha antibody Mab32 as a template (c.f. also US Patent 6090382).
- 克隆位点
- D2E7
- 亚型
- IgG1 kappa
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- 应用备注
- Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors.
- 说明
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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Scaling eukaryotic cell-free protein synthesis achieved with the versatile and high-yielding tobacco BY-2 cell lysate." in: Biotechnology and bioengineering, (2023) (PubMed).
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Scaling eukaryotic cell-free protein synthesis achieved with the versatile and high-yielding tobacco BY-2 cell lysate." in: Biotechnology and bioengineering, (2023) (PubMed).
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- 抗原
- TNF alpha (Adalimumab Biosimilar)
- Abstract
- TNF alpha (Adalimumab Biosimilar) 产品
- 别名
- DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, tumor necrosis factor antibody, TNF antibody
- 物质类
- Biosimilar
- 背景
- Tumor necrosis factor alpha
- UniProt
- P01375
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