Recombinant CD40L (Ruplizumab Biosimilar) 抗体
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- 抗原 See all CD40L (Ruplizumab Biosimilar) products
- CD40L (Ruplizumab Biosimilar)
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CD40L (Ruplizumab Biosimilar) antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Blocking Reagent (BR)
- 特异性
- The antibody binds to CD40L with an IC50 of 0.845 μg/mL.
- 产品特性
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OriginalSpeciesName: Human
OriginalFormat: IgG1
- 纯化方法
- Purified antibody.
- 纯度
- > 98 % as determined by SDS-PAGE
- 内毒素水平
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- 免疫原
- Human CD40L
- 克隆位点
- Hu5c8
- 亚型
- IgG kappa
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anti-CD40L (Ruplizumab Biosimilar) antibody
适用: 人 FACS, WB, BR 宿主: Human Monoclonal hu5c8 unconjugated Recombinant Antibody
anti-CD40L (Ruplizumab Biosimilar) antibodyResearch Grade 适用: 人 FACS, ELISA 宿主: Humanized Monoclonal unconjugated Recombinant Antibody
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- 应用备注
- The antibody binds specifically to CD40L, a surface receptor expressed on activated T cells which acts as a costimulatory molecule to trigger immune responses. The antibody neutralises CD40L function, as it blocks the interaction between CD40 and CD40L. When injected into cynomolgus monkeys, the original therapeutic antibody was found to have a T1/2 of 531? ±?155 hours.
- 说明
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- 抗原
- CD40L (Ruplizumab Biosimilar)
- Abstract
- CD40L (Ruplizumab Biosimilar) 产品
- 别名
- CD154 antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40 ligand antibody, CD40LG antibody
- 物质类
- Biosimilar
- 背景
- CD154, CD40 ligand, tumour necrosis factor ligand superfamily member 5, TNFSF5, tumour necrosis factor related activation protein, TRAP
- UniProt
- P29965
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