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Recombinant CD40L (Ruplizumab Biosimilar) 抗体

适用: 人 FACS, WB, BR 宿主: Human Monoclonal hu5c8 unconjugated Recombinant Antibody
产品编号 ABIN5668046
发货至: 中国
  • 抗原 See all CD40L (Ruplizumab Biosimilar) products
    CD40L (Ruplizumab Biosimilar)
    抗体类型
    Recombinant Antibody
    适用
    • 3
    • 1
    宿主
    • 1
    • 1
    • 1
    Human
    克隆类型
    • 3
    单克隆
    标记
    • 3
    This CD40L (Ruplizumab Biosimilar) antibody is un-conjugated
    应用范围
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Blocking Reagent (BR)
    特异性
    The antibody binds to CD40L with an IC50 of 0.845 μg/mL.
    产品特性

    OriginalSpeciesName: Human

    OriginalFormat: IgG1

    纯化方法
    Purified antibody.
    纯度
    > 98 % as determined by SDS-PAGE
    内毒素水平
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    免疫原
    Human CD40L
    克隆位点
    Hu5c8
    亚型
    IgG1 kappa
  • 应用备注
    The antibody binds specifically to CD40L, a surface receptor expressed on activated T cells which acts as a costimulatory molecule to trigger immune responses. The antibody neutralises CD40L function, as it blocks the interaction between CD40 and CD40L. When injected into cynomolgus monkeys, the original therapeutic antibody was found to have a T1/2 of 531? ±?155 hours.
    说明

    NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    CD40L (Ruplizumab Biosimilar)
    Abstract
    CD40L (Ruplizumab Biosimilar) 产品
    别名
    CD154 antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40 ligand antibody, CD40LG antibody
    物质类
    Biosimilar
    背景
    CD154, CD40 ligand, tumour necrosis factor ligand superfamily member 5, TNFSF5, tumour necrosis factor related activation protein, TRAP
    UniProt
    P29965
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