IL2 Receptor beta 抗体
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- 抗原 See all IL2 Receptor beta (IL2RB) 抗体
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL2 Receptor beta antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- 特异性
- The mouse monoclonal antibody TU27 recognizes an extracellular epitope of CD122 (IL-2R beta), a 70-75 kDa type I transmembrane glycoprotein constitutively expressed by NK cells and a T cell subset, and upregulated upon activation.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 内毒素水平
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- 免疫原
- TL-Mor cell line
- 克隆位点
- TU27
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product IL2RB Primary Antibody
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- 应用备注
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Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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- 抗原
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- 别名
- CD122 (IL2RB 产品)
- 别名
- IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
- 背景
- Interleukin 2 receptor subunit beta,CD122 (IL-2/IL-15R beta) constitutes together with CD132 (common gamma chain) and with CD25 (IL-2/IL15R alpha) the intermediate (CD122+CD132) and the high affinity (CD122+CD132+CD25) IL-2 and IL-15 receptor complex. CD122 is expressed on NK cells and lymphocytes, but at low level, unless the cell is activated. The cytoplasmic part of CD122 binds to Src-family and Jak-family kinases. The biological effect of CD122 ligation depends on whether IL-2 or IL-15 is bound to the receptor complex.,IL2RB, IL15RB, P70-75
- 基因ID
- 3560
- UniProt
- P14784
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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